| 名稱(chēng) | Recombinant Human IL-17 （IL-17A） |
| 型號(hào) | |
| 更新時(shí)間 | 2023-09-24 |
| 特點(diǎn) | 重組IL-17蛋白質(zhì),現(xiàn)在被稱(chēng)為IL-17A,是136為兩個(gè)氨基酸鏈,激活t細(xì)胞,分泌的促炎和造血基質(zhì)細(xì)胞誘導(dǎo)生產(chǎn)生物活性分子。重組人類(lèi)IL-17A 31.3 kDa disulfide-linked為兩個(gè)137氨基酸的多肽鏈。使用所有無(wú)動(dòng)物生產(chǎn)試劑。} |
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一.產(chǎn)品名稱(chēng)：Recombinant Human IL-17 (IL-17A)/Peprotech IL-17
二.Catalog Number:AF-200-17
三.Synonyms:IL-17, CTLA-8
四.Description:
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains. Manufactured using all non-animal reagents.
五.AA Sequence:
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:Measured by its ability to induce IL-6 production by NHDF cells using a concentration range of 0.5-1.5 ng/ml.
九.Cross Reactivity:Human, Cow
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手機(jī)：15311648455
地址：北京市海淀區(qū)廂黃旗2號(hào)樓1層4-179室